Hypoxia inducible factor 1α gene (<it>HIF-1α</it>) splice variants: potential prognostic biomarkers in breast cancer

<p>Abstract</p> <p>Background</p> <p>Hypoxia-inducible factor 1 (HIF-1) is a master transcriptional regulator of genes regulating oxygen homeostasis. The HIF-1 protein is composed of two HIF-1α and HIF-1β/aryl hydrocarbon receptor nuclear translocator (ARNT) subunits. T...

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Main Authors: Bonnier Pascal, Formisano-Tréziny Christine, Pradel Vincent, Pauly Vanessa, Picard Christophe, Silvy Monique, Beaufils Nathalie, Dales Jean-Philippe, Giusiano Sophie, Charpin Colette, Gabert Jean
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Medicine
Online Access:http://www.biomedcentral.com/1741-7015/8/44