Tauopathy Analysis in P301S Mouse Model of Alzheimer Disease Immunized with DNA and MVA Poxvirus-Based Vaccines Expressing Human Full-Length 4R2N or 3RC Tau Proteins

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a progressive memory loss and cognitive decline that has been associated with an accumulation in the brain of intracellular neurofibrillary tangles (NFTs) formed by hyperphosphorylated tau protein, and extracellular...

Full description

Bibliographic Details
Main Authors: Juan García-Arriaza, María Q. Marín, Jesús Merchán-Rubira, Sara M. Mascaraque, Miguel Medina, Jesús Ávila, Félix Hernández, Mariano Esteban
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/1/127