Lateral flow nucleic acid biosensor for sensitive detection of microRNAs based on the dual amplification strategy of duplex-specific nuclease and hybridization chain reaction.

MicroRNAs (miRNAs) constitute novel biomarkers for various diseases. Accurate and quantitative analysis of miRNA expression is critical for biomedical research and clinical theranostics. In this study, a method was developed for sensitive and specific detection of miRNAs via dual signal amplificatio...

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Bibliographic Details
Main Authors: Na Ying, Chuanjing Ju, Xiuwei Sun, Letian Li, Hongbiao Chang, Guangping Song, Zhongyi Li, Jiayu Wan, Enyong Dai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5612651?pdf=render