The role of pneumococcal extracellular vesicles on the pathophysiology of the kidney disease hemolytic uremic syndrome

ABSTRACT Streptococcus pneumoniae-induced hemolytic uremic syndrome (Sp-HUS) is a kidney disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. This disease is frequently underdiagnosed and its pathophysiology is poorly understood. In this work, we com...

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Bibliographic Details
Main Authors: Miriana Battista, Bianca Hoffmann, Yann Bachelot, Lioba Zimmermann, Laura Teuber, Aurélie Jost, Susanne Linde, Martin Westermann, Mario M. Müller, Hortense Slevogt, Sven Hammerschmidt, Marc Thilo Figge, Cláudia Vilhena, Peter F. Zipfel
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00142-23