Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation

Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation

Abstract The human thymus is the site of T‐cell maturation and induction of central tolerance. Hematopoietic stem cell (HSC)‐derived progenitors are recruited to the thymus from the fetal liver during early prenatal development and from bone marrow at later stages and postnatal life. The mechanism b...

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Bibliographic Details
Main Authors: Sara A. Watson, Yousef Javanmardi, Luca Zanieri, Somayeh Shahreza, Roberta Ragazzini, Paola Bonfanti, Emad Moeendarbary
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Bioengineering & Translational Medicine
Subjects:
drug discovery and development
lymphoid progenitors
microfluidic devices
organ‐mimetic systems
regenerative medicine
thymus on a chip
Online Access:https://doi.org/10.1002/btm2.10454

Internet

https://doi.org/10.1002/btm2.10454

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