Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia

Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia

BackgroundPreeclampsia (PE) is a pregnancy complication characterized by hypertension, proteinuria, endothelial dysfunction, and complement dysregulation. Placenta-derived extracellular vesicles (EVs), necessary in maternal–fetal communication, might contribute to PE pathogenesis. Moreover, neutroph...

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Main Authors: Alex Ramos, Lina Youssef, Patricia Molina, Sergi Torramadé-Moix, Julia Martinez-Sanchez, Ana Belen Moreno-Castaño, Miquel Blasco, Elena Guillén-Olmos, Blanca De Moner, Marc Pino, Marta Tortajada, Marta Camacho, Maria Borrell, Francesca Crovetto, Maria Jose Ramirez-Bajo, Pedro Ventura-Aguiar, Elisenda Banon-Maneus, Jordi Rovira, Gines Escolar, Enric Carreras, Eduard Gratacos, Maribel Diaz-Ricart, Fatima Crispi, Marta Palomo
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
pre-eclampsia
exosome
neutrophil activation
endothelium
complement membrane attack complex
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1488127/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1488127/full

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