Citrullinated isomer of myelin basic protein can induce inflammatory responses in astrocytes

Citrullinated isomer of myelin basic protein can induce inflammatory responses in astrocytes

Purpose: During the course of demyelinating inflammatory diseases, myelin-derived proteins, including myelin basic protein(MBP), are secreted into extracellular space. MBP shows extensive post-translational modifications, including deimination/citrullination. Deiminated MBP is structurally less orde...

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Bibliographic Details
Main Authors: Marika Chikviladze, Nino Mamulashvili, Maia Sepashvili, Nana Narmania, Jeremy Ramsden, Lali Shanshiashvili, David Mikeladze
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:IBRO Neuroscience Reports
Subjects:
Myelin basic protein
Glutamate
Deimination
Astrocytes
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S266724212302290X

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http://www.sciencedirect.com/science/article/pii/S266724212302290X

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