Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.
Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair. Lysine-specific histone demethylase 2 (LSD2) has been implicated in multiple types of human cancers. However, its functions remain poor...
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Public Library of Science (PLoS)
2021-07-01
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| श्रृंखला: | PLoS Genetics |
| ऑनलाइन पहुंच: | https://doi.org/10.1371/journal.pgen.1009715 |