Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma
Abstract Background Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases developed from trophoblasts. ASPP (Ankyrin-repeat, SH3-domain and proline-rich region containing protein) family proteins, ASPP1 and ASPP2, have been reported to be dysregulated in GTD. They modulate p53...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
|
Series: | BMC Cancer |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-6206-z |