Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn’s disease

In recent years it has become apparent that the epithelium is highly involved in inflammatory bowel disease (IBD) pathophysiology. The majority of gene expression studies of IBD are generated from heterogeneous biopsies, providing no distinction between immune cells, the epithelium and other mucosal...

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Bibliographic Details
Main Authors: Siri Sæterstad, Ann Elisabet Østvik, Elin Synnøve Røyset, Ingunn Bakke, Arne Kristian Sandvik, Atle van Beelen Granlund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916644/?tool=EBI