Association between Dietary Inflammatory Index and serum Klotho concentration among adults in the United States

Highlights 1. klotho deficiency linked to multiple premature-aging syndromes and a short lifespan 2. Proinflammatory cytokines, including TNF-α, IFN-γ, and IL-6, downregulate α-Klotho gene expression 3. Dietary Inflammatory Index was developed as a tool to determine the inflammatory potential of die...

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Bibliographic Details
Main Authors: Chichen Zhang, Zilong Zhang, Jiakun Li, Linghui Deng, Jiwen Geng, Kun Jin, Xiaonan Zheng, Shi Qiu, BiRong Dong
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Geriatrics
Subjects:
Online Access:https://doi.org/10.1186/s12877-022-03228-8