Protocol to create a murine subcutaneous air pouch for the study of monosodium urate crystal-induced gout

Summary: Monosodium urate (MSU) crystal deposition in articular joints and bursal tissue causes acute joint inflammation, which is a hallmark of gout. Here, we describe the steps necessary to create a subcutaneous air pouch on the back of mice that resembles this bursa-like space with a synovial lin...

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Bibliographic Details
Main Authors: Savita Devi, Christian Stehlik, Andrea Dorfleutner
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724000534