Antiretroviral Therapy Dampens Mucosal CD4<sup>+</sup> T Lamina Propria Lymphocytes Immune Activation in Long-Term Treated People Living with HIV-1

Antiretroviral Therapy Dampens Mucosal CD4<sup>+</sup> T Lamina Propria Lymphocytes Immune Activation in Long-Term Treated People Living with HIV-1

HIV infection is characterized by a severe deterioration of an immune cell-mediated response due to a progressive loss of CD4<sup>+</sup> T cells from gastrointestinal tract, with a preferential loss of IL-17 producing Th cells (Th17), a specific CD4<sup>+</sup> T cells subse...

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Bibliographic Details
Main Authors: Alessandro Lazzaro, Giuseppe Pietro Innocenti, Letizia Santinelli, Claudia Pinacchio, Gabriella De Girolamo, Paolo Vassalini, Gianfranco Fanello, Claudio Maria Mastroianni, Giancarlo Ceccarelli, Gabriella d’Ettorre
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Microorganisms
Subjects:
HIV-1
antiretroviral therapy
ART
GALT
immune activation
Th1
Online Access:https://www.mdpi.com/2076-2607/9/8/1624

Internet

https://www.mdpi.com/2076-2607/9/8/1624

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