Arginase induction and activation during ischemia and reperfusion and functional consequences for the heart

Induction and activation of arginase is among the fastest responses of the heart to ischemic events. Induction of arginase expression and enzyme activation under ischemic conditions shifts arginine consumption from nitric oxide formation (NO) to the formation of ornithine and urea. In the heart such...

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Bibliographic Details
Main Authors: Klaus-Dieter eSchlüter, Rainer eSchulz, Rolf eSchreckenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00054/full