An algorithm for network-based gene prioritization that encodes knowledge both in nodes and in links.

Candidate gene prioritization aims to identify promising new genes associated with a disease or a biological process from a larger set of candidate genes. In recent years, network-based methods - which utilize a knowledge network derived from biological knowledge - have been utilized for gene priori...

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Bibliographic Details
Main Authors: Chad Kimmel, Shyam Visweswaran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3834271?pdf=render