SOX2 and Bcl-2 as a Novel Prognostic Value in Hepatocellular Carcinoma Progression

SOX2 and Bcl-2 as a Novel Prognostic Value in Hepatocellular Carcinoma Progression

Sex-determining region Y-box 2 (SOX2) is a stem cell transcription factor and a major regulator of self-renewal and pluripotency of cancer stem cells (CSCs). In many types of cancer, SOX2 is dysregulated due to overexpression associated with tumor progression and low survival rate. Many HCC cases en...

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Bibliographic Details
Main Authors: Zahra Hosseini-khah, Mohammad Reza Babaei, Mohsen Tehrani, Magali Cucchiarini, Henning Madry, Abolghasem Ajami, Nasser Rakhshani, Alireza Rafiei, Behrooz Nikbin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Current Oncology
Subjects:
SRY-box 2 (SOX2)
cancer stem cell
hepatocellular carcinoma
Bcl-2
Bax
Online Access:https://www.mdpi.com/1718-7729/28/4/264

Internet

https://www.mdpi.com/1718-7729/28/4/264

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