IL-34 affects fibroblast-like synoviocyte proliferation, apoptosis and function by regulating IL-17

Abstract Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by proliferation and insufficient apoptosis of fibroblast-like synoviocytes (FLSs).The biology and functions of interleukin (IL)-34 are only beginning to be uncovered. We previously demonstrated IL-34 could upregulate...

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Bibliographic Details
Main Authors: Xin Li, Yimeng Lei, Ziyu Gao, Gang Wu, Wei Gao, Liping Xia, Jing Lu, Hui Shen
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95839-1