Genetic deletion of TREK-1 or TWIK-1/TREK-1 potassium channels does not alter the basic electrophysiological properties of mature hippocampal astrocytes in situ

Genetic deletion of TREK-1 or TWIK-1/TREK-1 potassium channels does not alter the basic electrophysiological properties of mature hippocampal astrocytes in situ

We have recently shown that a linear current-to-voltage (I-V) relationship of membrane conductance (passive conductance) reflects the intrinsic property of K+ channels in mature astrocytes. While passive conductance is known to underpin a highly negative and stable membrane potential (VM) essential...

Full description

Bibliographic Details
Main Authors: Yixing eDu, Conrad M. Kiyoshi, Qi eWang, Wei eWang, Bao Feng eMa, Catherine C. Alford, Shiying eZhong, Qi eWan, Haijun eChen, Eric Edward Lloyd, Robert M Bryan, Min eZhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Astrocytes
Hippocampus
patch-clamp recording
passive membrane conductance
TREK-1 potassium channel
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00013/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00013/full

Similar Items