(2-Hydroxy-3-Methoxybenzylidene)thiazolo[3,2-<i>a</i>]pyrimidines: Synthesis, Self-Assembly in the Crystalline Phase and Cytotoxic Activity

(2-Hydroxy-3-Methoxybenzylidene)thiazolo[3,2-<i>a</i>]pyrimidines: Synthesis, Self-Assembly in the Crystalline Phase and Cytotoxic Activity

A series of new 2-hydroxy-3-methoxybenzylidenethiazolo[3,2-<i>a</i>]pyrimidines with different aryl substituents at the 5 position are synthesized and characterized by <sup>1</sup>H/ <sup>13</sup>C NMR and IR-spectroscopy and mass-spectrometry, as well as single c...

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Bibliographic Details
Main Authors: Artem S. Agarkov, Anna A. Nefedova, Elina R. Gabitova, Dilyara O. Mingazhetdinova, Alexander S. Ovsyannikov, Daut R. Islamov, Syumbelya K. Amerhanova, Anna P. Lyubina, Alexandra D. Voloshina, Igor A. Litvinov, Svetlana E. Solovieva, Igor S. Antipin
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
thiazolo[3,2-<i>a</i>]pyrimidines
crystal structure
non-covalent interactions
halogen and hydrogen bonding
chiral discrimination
cytotoxicity
Online Access:https://www.mdpi.com/1422-0067/24/3/2084

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https://www.mdpi.com/1422-0067/24/3/2084

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