Optimization of a high-throughput whole blood expression profiling methodology and its application to assess the pharmacodynamics of interferon (IFN) beta-1a or polyethylene glycol-conjugated IFN beta-1a in healthy clinical trial subjects

<p>Abstract</p> <p>Background</p> <p>Clinical trials offer a unique opportunity to study human disease and response to therapy in a highly controlled setting. The application of high-throughput expression profiling to peripheral blood from clinical trial subjects could...

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Bibliographic Details
Main Authors: Allaire Normand E, Bushnell Steven E, Bienkowska Jadwiga, Brock Graham, Carulli John
Format: Article
Language:English
Published: BMC 2013-01-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/6/8