Neurobehavioral changes and activation of neurodegenerative apoptosis on long-term consumption of aspartame in the rat brain

Though several studies on toxic effect of aspartame metabolite have been studied, there are scanty data on whether aspartame exposure administration could release formate, a methanol metabolite thereby inducing oxidative stress and neurodegeneration in brain discrete region. To mimic the human metha...

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Bibliographic Details
Main Authors: I. Ashok, Dapkupar wankhar, Wankupar wankhar, R. Sheeladevi
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Journal of Nutrition & Intermediary Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352385915300025