Persistently high antibody responses after AS03-adjuvanted H1N1pdm09 vaccine: Dissecting the HA specific antibody response

Abstract Current influenza vaccines have a suboptimal effectiveness. The introduction of a novel A/H1N1 influenza virus in 2009 (H1N1pdm09) provided a unique opportunity to study the humoral response to the AS03-adjuvanted H1N1pdm09 vaccine and repeated annual vaccination with the homologous virus i...

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Bibliographic Details
Main Authors: Anders Madsen, Åsne Jul-Larsen, Mai-Chi Trieu, Florian Krammer, Rebecca J. Cox
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00308-5