Oridonin impedes breast cancer growth by blocking cells in S phase and inhibiting the PI3K/AKT/mTOR signaling pathway

Oridonin impedes breast cancer growth by blocking cells in S phase and inhibiting the PI3K/AKT/mTOR signaling pathway

Breast cancer is one of the most common cancers. Oridonin, a traditional Chinese medicine, is believed to inhibit tumor growth, but its particular effects on breast cancer remain unknown. In this study, we examined oridonin's effects on 4T1, MCF-7, and MDAMB-231 cellular activity using CCK8. Sc...

Full description

Bibliographic Details
Main Authors: Weijie Zhang, Lei Shi, Wei Zhou, Xin Liu, Yuan Xi, Xinyin Wang, Ya Li, Xia Xu, Youcai Tang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Oridonin
Breast cancer
Metabolomics
Amino acid metabolism
PI3K/AKT/mTOR signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023052544

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023052544

Similar Items