HMOX1 STR polymorphism and malaria: an analysis of a large clinical dataset

Abstract Background Inducible expression of heme oxygenase-1 (encoded by the gene HMOX1) may determine protection from heme released during malaria infections. A variable length, short tandem GT(n) repeat (STR) in HMOX1 that may influence gene expression has been associated with outcomes of human ma...

Full description

Bibliographic Details
Main Authors: Fergus Hamilton, Ruth Mitchell, Aubrey Cunnington, Peter Ghazal, Nicholas J. Timpson
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Malaria Journal
Online Access:https://doi.org/10.1186/s12936-022-04352-x