Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control

Enzymatically dissociated muscle fibers display rapid dedifferentiation and impaired mitochondrial calcium control

Summary: Cells rapidly lose their physiological phenotype upon disruption of their extracellular matrix (ECM)-intracellular cytoskeleton interactions. By comparing adult mouse skeletal muscle fibers, isolated either by mechanical dissection or by collagenase-induced ECM digestion, we investigated ac...

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Bibliographic Details
Main Authors: Charlotte Gineste, Sonia Youhanna, Sabine U. Vorrink, Sara Henriksson, Andrés Hernández, Arthur J. Cheng, Thomas Chaillou, Andreas Buttgereit, Dominik Schneidereit, Oliver Friedrich, Kjell Hultenby, Joseph D. Bruton, Niklas Ivarsson, Linda Sandblad, Volker M. Lauschke, Håkan Westerblad
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Cellular physiology
Cell biology
Functional aspects of cell biology
Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222019265

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http://www.sciencedirect.com/science/article/pii/S2589004222019265

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