Mesenchymal stromal/stem cell tissue source and in vitro expansion impact extracellular vesicle protein and miRNA compositions as well as angiogenic and immunomodulatory capacities
Abstract Recently, therapies utilizing extracellular vesicles (EVs) derived from mesenchymal stromal/stem cells (MSCs) have begun to show promise in clinical trials. However, EV therapeutic potential varies with MSC tissue source and in vitro expansion through passaging. To find the optimal MSC sour...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-08-01
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Series: | Journal of Extracellular Vesicles |
Subjects: | |
Online Access: | https://doi.org/10.1002/jev2.12472 |