BRCA1/2 NGS Somatic Testing in Clinical Practice: A Short Report

BRCA1/2 NGS Somatic Testing in Clinical Practice: A Short Report

High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of all ovarian carcinomas. HGSOC harboring <i>BRCA1</i>/<i>2</i> germline or somatic mutations are sensitive to the poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPi). Therefore, detecting t...

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Bibliographic Details
Main Authors: Francesco Pepe, Pasquale Pisapia, Gianluca Russo, Mariantonia Nacchio, Pierlorenzo Pallante, Elena Vigliar, Carmine De Angelis, Luigi Insabato, Claudio Bellevicine, Sabino De Placido, Giancarlo Troncone, Umberto Malapelle
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Genes
Subjects:
HGSOC
molecular pathology
<i>BRCA1/2</i>
PARPi
NGS
Online Access:https://www.mdpi.com/2073-4425/12/12/1917

Internet

https://www.mdpi.com/2073-4425/12/12/1917

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