Inhibition of LSD1 promotes the differentiation of human induced pluripotent stem cells into insulin-producing cells

Inhibition of LSD1 promotes the differentiation of human induced pluripotent stem cells into insulin-producing cells

Abstract Background Human induced pluripotent stem cells (hiPSCs) represent a potentially unlimited source of pancreatic endocrine lineage cells. Although insulin-producing β cells derived from hiPSCs have been successfully induced, much work remains to be done to achieve mature β cells. Lysine-spec...

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Bibliographic Details
Main Authors: Xiao-Fei Yang, Shu-Yan Zhou, Ce Wang, Wei Huang, Ning Li, Fei He, Fu-Rong Li
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Stem Cell Research & Therapy
Subjects:
LSD1
Human induced pluripotent stem cells
Insulin-producing cells
Differentiation
Diabetes
Online Access:http://link.springer.com/article/10.1186/s13287-020-01694-8

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http://link.springer.com/article/10.1186/s13287-020-01694-8

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