Doxorubicin-Induced Cardiac Toxicity Is Mediated by Lowering of Peroxisome Proliferator-Activated Receptor δ Expression in Rats

The present study investigates the changes of peroxisome proliferator-activated receptors δ (PPARδ) expression and troponin phosphorylation in heart of rats which were treated with doxorubicin (DOX). Wistar rats which were treated with DOX according to a previous method. The protein levels of PPARδ...

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Bibliographic Details
Main Authors: Zhih-Cherng Chen, Li-Jen Chen, Juei-Tang Cheng
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2013/456042