Memantine ameliorates motor impairments and pathologies in a mouse model of neuromyelitis optica spectrum disorders

Memantine ameliorates motor impairments and pathologies in a mouse model of neuromyelitis optica spectrum disorders

Abstract Background Neuromyelitis optica spectrum disorders (NMOSD) are central nervous system (CNS) autoimmune inflammatory demyelinating diseases characterized by recurrent episodes of acute optic neuritis and transverse myelitis. Aquaporin-4 immunoglobulin G (AQP4-IgG) autoantibodies, which targe...

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Bibliographic Details
Main Authors: Leung-Wah Yick, Chi-Ho Tang, Oscar Ka-Fai Ma, Jason Shing-Cheong Kwan, Koon-Ho Chan
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Neuroinflammation
Subjects:
Aquaporin-4
Autoimmunity
Memantine
Neuroinflammation
Neuromyelitis optica
Online Access:http://link.springer.com/article/10.1186/s12974-020-01913-2

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http://link.springer.com/article/10.1186/s12974-020-01913-2

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