PNPLA3 genotype and fibrosis-4 index predict cardiovascular diseases of Japanese patients with histopathologically-confirmed NAFLD

PNPLA3 genotype and fibrosis-4 index predict cardiovascular diseases of Japanese patients with histopathologically-confirmed NAFLD

Abstract Background Reliable noninvasive predictors of the top three causes of death [cardiovascular diseases (CVDs), malignancies, and liver-related events in patients with non-alcoholic fatty liver disease (NAFLD)] have not yet been determined. Methods We retrospectively investigated the incidence...

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Bibliographic Details
Main Authors: Norio Akuta, Yusuke Kawamura, Yasuji Arase, Satoshi Saitoh, Shunichiro Fujiyama, Hitomi Sezaki, Tetsuya Hosaka, Masahiro Kobayashi, Mariko Kobayashi, Yoshiyuki Suzuki, Fumitaka Suzuki, Kenji Ikeda, Hiromitsu Kumada
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Gastroenterology
Subjects:
Nonalcoholic fatty liver disease
Nonalcoholic steatohepatitis
Cardiovascular diseases
Malignancies
Liver-related events
FIB-4 index
Online Access:https://doi.org/10.1186/s12876-021-02020-z

Internet

https://doi.org/10.1186/s12876-021-02020-z

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