A Noncanonical Autophagy Pathway Restricts <named-content content-type="genus-species">Toxoplasma gondii</named-content> Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells
ABSTRACT A core set of autophagy proteins is required for gamma interferon (IFN-γ)-mediated clearance of Toxoplasma gondii in the mouse because of their control of several downstream effectors, including immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs). However, these effectors...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2015-10-01
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Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01157-15 |