MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases.

MicroRNA-4723 inhibits prostate cancer growth through inactivation of the Abelson family of nonreceptor protein tyrosine kinases.

The Abelson (c-Abl) proto-oncogene encodes a highly conserved nonreceptor protein tyrosine kinase that plays a role in cell proliferation, differentiation, apoptosis and cell adhesion. c-Abl represents a specific anti-cancer target in prostate cancer as aberrant activity of this kinase has been impl...

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Bibliographic Details
Main Authors: Sumit Arora, Sharanjot Saini, Shinichiro Fukuhara, Shahana Majid, Varahram Shahryari, Soichiro Yamamura, Takeshi Chiyomaru, Guoren Deng, Yuichiro Tanaka, Rajvir Dahiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815229?pdf=render

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http://europepmc.org/articles/PMC3815229?pdf=render

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