Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Abstract Various mutations in the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene are associated with neurodevelopmental and neuropsychiatric disorders. Thus far, synaptic abnormalities in multiple brain regions, including the hippocampus, prefrontal cortex, striatum, and ventral tegmental a...

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Bibliographic Details
Main Authors: Chunmei Jin, Hyojin Kang, Shinhyun Kim, Yinhua Zhang, Yeunkum Lee, Yoonhee Kim, Kihoon Han
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Molecular Brain
Subjects:
Shank3
Hypothalamus
Transcriptome
Online Access:http://link.springer.com/article/10.1186/s13041-018-0413-4

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http://link.springer.com/article/10.1186/s13041-018-0413-4

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