Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats

Potassium Intake Prevents the Induction of the Renin-Angiotensin System and Increases Medullary ACE2 and COX-2 in the Kidneys of Angiotensin II-Dependent Hypertensive Rats

In angiotensin II (Ang II)-dependent hypertensive rats there is an increased expression of proximal tubule angiotensinogen (AGT), collecting duct renin and angiotensin converting enzyme (ACE), which contributes to intratubular Ang II formation. Ang II acts on Ang II type 1 receptors promoting sodium...

Full description

Bibliographic Details
Main Authors: Alexis A. Gonzalez, Matias Gallardo, Carlos Cespedes, Carlos P. Vio
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
potassium
blood pressure
renin
angiotensin
hypertension
kallikrein
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01212/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01212/full

Similar Items