The stability of a stochastic CaMKII switch: dependence on the number of enzyme molecules and protein turnover.

Molecular switches have been implicated in the storage of information in biological systems. For small structures such as synapses, these switches are composed of only a few molecules and stochastic fluctuations are therefore of importance. Such fluctuations could potentially lead to spontaneous swi...

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Bibliographic Details
Main Authors: Paul Miller, Anatol M Zhabotinsky, John E Lisman, Xiao-Jing Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1069645?pdf=render