A class of secreted mammalian peptides with potential to expand cell-cell communication

Abstract Peptide hormones and neuropeptides are signaling molecules that control diverse aspects of mammalian homeostasis and physiology. Here we provide evidence for the endogenous presence of a sequence diverse class of blood-borne peptides that we call “capped peptides.” Capped peptides are fragm...

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Bibliographic Details
Main Authors: Amanda L. Wiggenhorn, Hind Z. Abuzaid, Laetitia Coassolo, Veronica L. Li, Julia T. Tanzo, Wei Wei, Xuchao Lyu, Katrin J. Svensson, Jonathan Z. Long
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43857-0