(-)-α-Bisabolol inhibits D-Gal-induced HSF cellular senescence in vitro and prevents skin aging in vivo by reducing SASP

Objective(s): To study the anti-aging effect of (-)-α-bisabolol ((-)-α-bis) on the skin and preliminarily clarify its mechanism. Materials and Methods: Human skin fibroblasts (HSF) were induced senescence by D-Galactose. Senescence β-galactosidase staining was utilized to evaluate the senescence of...

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Bibliographic Details
Main Authors: Meixing He, Panyu Zhou, Hankun Chen, Junhong Zhang, Yating Zhang, Xianhui Zheng, Wei Zhu, Ling Han
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2024-08-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_24287_7d2cc2f76a33b422b2cd54531c65ea96.pdf