Inhalable CAR-T cell-derived exosomes as paclitaxel carriers for treating lung cancer

Abstract Background Non-small cell lung cancer (NSCLC) is a worldwide health threat with high annual morbidity and mortality. Chemotherapeutic drugs such as paclitaxel (PTX) have been widely applied clinically. However, systemic toxicity due to the non-specific circulation of PTX often leads to mult...

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Bibliographic Details
Main Authors: Wei Zheng, Tianchuan Zhu, Lantian Tang, Zhijian Li, Guanmin Jiang, Xi Huang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04206-3