Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies

Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies

Osteoblast-derived extracellular vesicles (EV) are a collection of secreted (sEVs) and matrix-bound nanoparticles that function as foci for mineral nucleation and accumulation. Due to the fact sEVs can be isolated directly from the culture medium of mineralizing osteoblasts, there is growing interes...

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Bibliographic Details
Main Authors: Owen G. Davies, Sophie C. Cox, Ioannis Azoidis, Adam J. A. McGuinness, Megan Cooke, Liam M. Heaney, Edward T. Davis, Simon W. Jones, Liam M. Grover
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
vesicle
mineralization
annexin
collagen
osteoblast
nano
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00092/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00092/full

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