TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex

TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated the as yet unknown roles of calcium signaling and autophagy regulatory protei...

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Bibliographic Details
Main Authors: Kelly Airiau, Pierre Vacher, Olivier Micheau, Valerie Prouzet-Mauleon, Guido Kroemer, Mohammad Amin Moosavi, Mojgan Djavaheri-Mergny
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
ATRA
ATG7
autophagy
cancer
CRAC channels
DISC
Online Access:https://www.mdpi.com/2073-4409/11/1/57

Internet

https://www.mdpi.com/2073-4409/11/1/57

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