A molecular signature of lung-resident CD8+ T cells elicited by subunit vaccination

Abstract Natural infection as well as vaccination with live or attenuated viruses elicit tissue resident, CD8+ memory T cell (Trm) response. Trm cells so elicited act quickly upon reencounter with the priming agent to protect the host. These Trm cells express a unique molecular signature driven by t...

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Bibliographic Details
Main Authors: Naveenchandra Suryadevara, Amrendra Kumar, Xiang Ye, Meredith Rogers, John V. Williams, John T. Wilson, John Karijolich, Sebastian Joyce
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21620-7