Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts.

Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts.

Brugia malayi is a human filarial nematode responsible for elephantiasis, a debilitating condition that is part of a broader spectrum of diseases called filariasis, including lymphatic filariasis and river blindness. Almost all filarial nematode species infecting humans live in mutualism with Wolbac...

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Bibliographic Details
Main Authors: Germain Chevignon, Vincent Foray, Mercedes Maria Pérez-Jiménez, Silvia Libro, Matthew Chung, Jeremy M Foster, Frédéric Landmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008935

Internet

https://doi.org/10.1371/journal.pntd.0008935

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