Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells

Abstract MicroRNA miR-155 is an important regulatory molecule in the immune system and is highly expressed and functional in Th17 cells, a subset of CD4+ T helper cells which are key players in autoimmune diseases. Small molecules that can modulate miR-155 may potentially provide new therapeutic ave...

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Bibliographic Details
Main Authors: Anju Singh, Myagmarjav Dashynam, Bryan Chim, Thelma M. Escobar, Xiuhuai Liu, Xin Hu, Samarjit Patnaik, Xin Xu, Noel Southall, Juan Marugan, Ajit Jadhav, Vanja Lazarevic, Stefan A. Muljo, Marc Ferrer
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90944-7

Internet

https://doi.org/10.1038/s41598-021-90944-7

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