Deciphering epigenomic code for cell differentiation using deep learning

Abstract Background Although DNA sequence plays a crucial role in establishing the unique epigenome of a cell type, little is known about the sequence determinants that lead to the unique epigenomes of different cell types produced during cell differentiation. To fill this gap, we employed two types...

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Bibliographic Details
Main Authors: Pengyu Ni, Zhengchang Su
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-019-6072-8