Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss

Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss

The transcription factor EGR1 is instrumental in numerous neurological processes, encompassing learning and memory as well as the reaction to stress. Egr1 complete knockout mice demonstrate decreased depressive or anxiety-like behavior and impaired performance in spatial learning and memory. Neverth...

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Bibliographic Details
Main Authors: Cody Swilley, Yu Lin, Yuze Zheng, Xiguang Xu, Min Liu, Timothy Jarome, Georgia E. Hodes, Hehuang Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Neuroscience
Subjects:
sex difference
Egr1
nestin
RNA-seq
hippocampus
behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1240209/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1240209/full

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