Anti-Claudin Treatments in Gastroesophageal Adenocarcinoma: Mainstream and Upcoming Strategies

Anti-Claudin Treatments in Gastroesophageal Adenocarcinoma: Mainstream and Upcoming Strategies

Claudins (CLDNs) are a multigene family of proteins and the principal components of tight junctions (TJs), which normally mediate cell–cell adhesion and selectively allow the paracellular flux of ions and small molecules between cells. Downregulation of claudin proteins increases the paracellular pe...

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Bibliographic Details
Main Authors: Giulia Grizzi, Kostantinos Venetis, Nerina Denaro, Maria Bonomi, Andrea Celotti, Antonia Pagkali, Jens Claus Hahne, Gianluca Tomasello, Fausto Petrelli, Nicola Fusco, Michele Ghidini
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Clinical Medicine
Subjects:
gastric cancer
claudins
anti-claudin 18.2
esophageal cancer
zolbetuximab
car-T cells
Online Access:https://www.mdpi.com/2077-0383/12/8/2973

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https://www.mdpi.com/2077-0383/12/8/2973

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