Palladium Iodide Catalyzed Multicomponent Carbonylative Synthesis of 2-(4-Acylfuran-2-yl)acetamides

Palladium Iodide Catalyzed Multicomponent Carbonylative Synthesis of 2-(4-Acylfuran-2-yl)acetamides

2-Propargyl-1,3-dicarbonyl compounds have been carbonylated under oxidative conditions and with the catalysis of the PdI<sub>2</sub>/KI catalytic system to selectively afford previously unreported 2-(4-acylfuran-2-yl)acetamides in fair to good yields (54–81%) over 19 examples. The proces...

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Bibliographic Details
Main Authors: Ida Ziccarelli, Lucia Veltri, Tommaso Prestia, Roberta Amuso, Maria A. Chiacchio, Raffaella Mancuso, Bartolo Gabriele
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Molecules
Subjects:
alkynes
amides
aminocarbonylation
carbonylation
C–H activation
conjugate addition
Online Access:https://www.mdpi.com/1420-3049/28/19/6764

Internet

https://www.mdpi.com/1420-3049/28/19/6764

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