Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets.

Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets.

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Recent evidence suggests that circadian clocks ensure temporal orchestration of lipid homeostasis and play a role in pathophysiology of metabolic diseases in humans, including type 2 diabetes (T2D). Nevertheless, circadian regulation of lipid metabolism in human pancreatic islets has not been explor...

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Bibliographic Details
Main Authors: Volodymyr Petrenko, Flore Sinturel, Ursula Loizides-Mangold, Jonathan Paz Montoya, Simona Chera, Howard Riezman, Charna Dibner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001725

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https://doi.org/10.1371/journal.pbio.3001725

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