CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

Abstract Background CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. Results Here we showed two kinds of programmable base editing systems, cytosine base editors (CB...

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Bibliographic Details
Main Authors: Yufeng Luo, Mei Ge, Bolun Wang, Changhong Sun, Junyi Wang, Yuyang Dong, Jianzhong Jeff Xi
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Microbial Cell Factories
Subjects:
CRISPR/Cas9
Cytosine base editors
Adenine base editors
Rhodobacter sphaeroides
Coenzyme Q10
Online Access:http://link.springer.com/article/10.1186/s12934-020-01345-w

Internet

http://link.springer.com/article/10.1186/s12934-020-01345-w

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